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Title
Date
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Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations
(358 downloads)
21 Jun 2018
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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells.
(377 downloads)
17 May 2018
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Prognostic scoring systems for myelodysplastic syndromes (MDS) in a population-based setting: a report from the Swedish MDS register.
(394 downloads)
29 Apr 2018
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Sipa1 deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm.
(323 downloads)
13 Mar 2018
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Health-related quality of life in lower-risk MDS patients compared with age- and sex-matched reference populations: a European LeukemiaNet study.
(341 downloads)
06 Mar 2018
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Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.
(337 downloads)
14 Feb 2018
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Prognostic impact of a suboptimal number of analyzed metaphases in normal karyotype lower-risk MDS.
(319 downloads)
31 Jan 2018
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Megakaryocytes harbour the del(5q) abnormality despite complete clinical and cytogenetic remission induced by lenalidomide treatment.
(349 downloads)
29 Jan 2018
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Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes.
(358 downloads)
09 Nov 2017
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Gene expression and risk of leukemic transformation in myelodysplasia.
(367 downloads)
02 Nov 2017
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Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes.
(348 downloads)
18 Jul 2017
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Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q).
(347 downloads)
26 Jun 2017
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Ex Vivo expanded adaptive NK cells effectively kill primary acute lymphoblastic leukemia cells
(560 downloads)
21 Jun 2017
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SF3B1-initiating Mutations in MDS with ring sideroblasts target lymphomyeloid hematopoietic stem cells
(540 downloads)
20 Jun 2017
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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
(546 downloads)
01 Jun 2017
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Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance
(550 downloads)
20 May 2017
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Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease
(582 downloads)
25 Apr 2017
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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
(599 downloads)
24 Apr 2017
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Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel
(719 downloads)
30 Mar 2017
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Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome
(557 downloads)
30 Mar 2017
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Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations
(523 downloads)
30 Mar 2017
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Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
(615 downloads)
15 Mar 2017
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Evaluating variant calling tools for non-matched next-generation sequencing data
(606 downloads)
24 Feb 2017
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Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia
(601 downloads)
16 Feb 2017
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Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality
(695 downloads)
24 Sep 2016
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GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome
(801 downloads)
01 Jul 2016
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Impact of socioeconomic status on disease phenotype, genomic landscape and outcomes in myelodysplastic syndromes
(497 downloads)
01 Jul 2016
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Mutations in histone modulators are associated with prolonged survival during azacitidine therapy
(962 downloads)
19 Apr 2016
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The European Hematology Association Roadmap for European Hematology Research: a consensus document
(563 downloads)
29 Feb 2016
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Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts
(890 downloads)
17 Nov 2015
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Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome
(695 downloads)
27 Oct 2015
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Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry
(822 downloads)
21 Oct 2015
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SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts
(1069 downloads)
Popular
21 Oct 2015
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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells
(411 downloads)
01 Aug 2015
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High-throughput mutational screening adds clinically important information in myelodysplastic syndromes and secondary or therapy-related acute myeloid leukemia
(830 downloads)
01 Jun 2015
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Self-perception of symptoms of anemia and fatigue before and after blood transfusions in patients with myelodysplastic syndromes
(873 downloads)
01 Apr 2015
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Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes
(450 downloads)
09 Jan 2015
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Specific scoring systems to predict survival of patients with high-risk myelodysplastic syndrome (MDS) and de novo acute myeloid leukemia (AML) after intensive antileukemic treatment based on results of the EORTC-GIMEMA AML-10 and intergroup CRIANT studie
(678 downloads)
01 Jan 2015
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Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes
(419 downloads)
01 Jan 2015
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Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study
(805 downloads)
21 Nov 2014
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Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia
(473 downloads)
28 Aug 2014
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Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes
(426 downloads)
04 Aug 2014
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A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome
(1006 downloads)
Popular
19 Jun 2014
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Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
(445 downloads)
16 Jun 2014
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A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine
(854 downloads)
14 Jun 2014
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A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome
(514 downloads)
01 Jun 2014
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p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q)
(442 downloads)
01 Jun 2014
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Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
(950 downloads)
15 May 2014
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Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial
(854 downloads)
07 May 2014
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Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation
(820 downloads)
21 Feb 2014
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Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients
(763 downloads)
21 Feb 2014
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Challenges of phase III trial design for novel treatments in diseases with no standard treatment: the AZA-001 myelodysplasia study model
(417 downloads)
01 Feb 2014
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Clinical and biological implications of driver mutations in myelodysplastic syndromes
(991 downloads)
21 Nov 2013
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Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet
(464 downloads)
24 Oct 2013
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Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes
(767 downloads)
01 Oct 2013
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Role of reduced-intensity conditioning allogeneic hematopoietic stem-cell transplantation in older patients with de novo myelodysplastic syndromes: an international collaborative decision analysis
(327 downloads)
20 Jul 2013
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A multivariate analysis of the relationship between response and survival among patients with higher-risk myelodysplastic syndromes treated within azacitidine or conventional care regimens in the randomized AZA-001 trial
(343 downloads)
01 Jul 2013
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Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions
(392 downloads)
01 May 2013
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The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts
(393 downloads)
01 Apr 2013
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Lenalidomide does not increase AML progression risk in RBC transfusion-dependent patients with Low- or Intermediate-1-risk MDS with del(5q): a comparative analysis
(364 downloads)
01 Apr 2013
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Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1
(379 downloads)
01 Mar 2013
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Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group
(312 downloads)
01 Mar 2013
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Bone marrow dendritic cells are reduced in patients with high-risk myelodysplastic syndromes
(429 downloads)
01 Mar 2013
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Downregulation but lack of promoter hypermethylation or somatic mutations of the potential tumor suppressor CXXC5 in MDS and AML with deletion 5q
(337 downloads)
01 Mar 2013
pdf
Evaluation of Azacitidine in transfusion-dependent, Epo-refractory patients with lower-risk MDS
( pdf, 83 KB )
(1022 downloads)
Popular
18 Jun 2012
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Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML
(416 downloads)
05 Jan 2012
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Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
(416 downloads)
08 Dec 2011
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Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks
(354 downloads)
17 Nov 2011
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Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
(352 downloads)
13 Oct 2011
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Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
(362 downloads)
01 Oct 2011
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Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes
(335 downloads)
15 Jun 2011
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TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression
(366 downloads)
20 May 2011
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Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities
(709 downloads)
31 Mar 2011
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Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes
(341 downloads)
01 Dec 2010
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Significance of JAK2 and TET2 mutations in myelodysplastic syndromes
(840 downloads)
18 Sep 2010
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Persistent malignant stem cells in del(5q) myelodysplasia in remission
(357 downloads)
09 Sep 2010
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Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine
(335 downloads)
01 Aug 2010
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Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy
(718 downloads)
20 May 2010
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Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C
(339 downloads)
01 Apr 2010
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Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
(348 downloads)
01 Feb 2010
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Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression
(320 downloads)
01 Dec 2009
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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
(717 downloads)
18 Feb 2009
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Erythropoietin and G-CSF treatment associated with improved survival in myelodysplastic syndrome
(767 downloads)
18 Sep 2008
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Supportive care, growth factors, and new therapies in myelodysplastic syndromes
(749 downloads)
18 Sep 2008
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Azacitidine prolongs overall survival and reduces infections and hospitalizations in patients with WHO-defined acute myeloid leukaemia compared with conventional care regimens: an update
(340 downloads)
01 Jan 2008
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The effects of continued azacitidine treatment cycles on response in higher risk patients with myelodysplastic syndromes: an update
(327 downloads)
01 Jan 2008
pdf
Negative Effect of DNA Hypermethylation on the Outcome of Intensive Chemotherapy in Older Patients with High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia following Myelodysplastic Syndrome
(566 downloads)
01 Dec 2007
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The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes
(319 downloads)
15 Oct 2007
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Antithymocyte globulin and cyclosporine A as combination therapy for low-risk non-sideroblastic myelodysplastic syndromes
(667 downloads)
18 Sep 2006
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Antiapoptotic role of growth factors in the myelodysplastic syndromes: concordance between in vitro and in vivo observations
(317 downloads)
01 Sep 2005
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Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes
(309 downloads)
01 Jul 2005
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Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF
(722 downloads)
19 Apr 2005
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The WHO classification of MDS does make a difference
(701 downloads)
01 May 2004
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No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease
(640 downloads)
24 Apr 2003
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A validated decision model for treating the anaemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life
(657 downloads)
23 Sep 2002
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Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8
(306 downloads)
01 Jul 2002
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Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level
(323 downloads)
15 Sep 2000
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Myelodysplastisk syndrom
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Tietoa myelodysplastisesta syndroomasta
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Myelodysplastic syndrome
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Myelodysplastisk syndrom
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Myelodysplastiskt syndrom