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Title
Date
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Male sex and the pattern of recurrent myeloid mutations are strong independent predictors of blood transfusion intensity in patients with myelodysplastic syndromes.
(889 downloads)
22 Jul 2020
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TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.
(893 downloads)
22 Jul 2020
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A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes.
(875 downloads)
22 Jul 2020
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Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.
(851 downloads)
22 Jul 2020
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Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.
(977 downloads)
22 Jul 2020
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Myelodysplastic syndromes: moving towards personalized management.
(948 downloads)
22 Jul 2020
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Prognostic scoring systems and comorbidities in chronic myelomonocytic leukaemia: a nationwide population-based study.
(819 downloads)
22 Jul 2020
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SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS.
(989 downloads)
22 Jul 2020
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Clonal hematopoiesis in elderly twins: concordance, discordance and survival.
(961 downloads)
21 Jul 2020
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Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes.
(928 downloads)
21 Jul 2020
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Clonal hematopoiesis evolves from pre-treatment clones and stabilizes after end of chemotherapy in patients with MCL
(834 downloads)
21 Jul 2020
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Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity are Linked to Clinical Responses to 5-Azacytidine.
(899 downloads)
21 Jul 2020
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Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: A national population-based cohort study
(871 downloads)
21 Jul 2020
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Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations
(1538 downloads)
Popular
21 Jun 2018
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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells.
(1495 downloads)
Popular
17 May 2018
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Prognostic scoring systems for myelodysplastic syndromes (MDS) in a population-based setting: a report from the Swedish MDS register.
(1571 downloads)
Popular
29 Apr 2018
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Sipa1 deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm.
(1337 downloads)
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13 Mar 2018
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Health-related quality of life in lower-risk MDS patients compared with age- and sex-matched reference populations: a European LeukemiaNet study.
(1389 downloads)
Popular
06 Mar 2018
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Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.
(1431 downloads)
Popular
14 Feb 2018
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Prognostic impact of a suboptimal number of analyzed metaphases in normal karyotype lower-risk MDS.
(1408 downloads)
Popular
31 Jan 2018
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Megakaryocytes harbour the del(5q) abnormality despite complete clinical and cytogenetic remission induced by lenalidomide treatment.
(1324 downloads)
Popular
29 Jan 2018
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Labile plasma iron levels predict survival in patients with lower-risk myelodysplastic syndromes.
(1397 downloads)
Popular
09 Nov 2017
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Gene expression and risk of leukemic transformation in myelodysplasia.
(1365 downloads)
Popular
02 Nov 2017
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Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes.
(1386 downloads)
Popular
18 Jul 2017
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Clinical characteristics and outcomes according to age in lenalidomide-treated patients with RBC transfusion-dependent lower-risk MDS and del(5q).
(1320 downloads)
Popular
26 Jun 2017
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Ex Vivo expanded adaptive NK cells effectively kill primary acute lymphoblastic leukemia cells
(1667 downloads)
Popular
21 Jun 2017
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SF3B1-initiating Mutations in MDS with ring sideroblasts target lymphomyeloid hematopoietic stem cells
(1525 downloads)
Popular
20 Jun 2017
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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
(1623 downloads)
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01 Jun 2017
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Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance
(1494 downloads)
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20 May 2017
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Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease
(1553 downloads)
Popular
25 Apr 2017
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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes
(1595 downloads)
Popular
24 Apr 2017
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Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel
(1754 downloads)
Popular
30 Mar 2017
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Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome
(1485 downloads)
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30 Mar 2017
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Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations
(1547 downloads)
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30 Mar 2017
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Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
(1591 downloads)
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15 Mar 2017
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Evaluating variant calling tools for non-matched next-generation sequencing data
(1536 downloads)
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24 Feb 2017
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Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia
(1653 downloads)
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16 Feb 2017
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Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality
(1573 downloads)
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24 Sep 2016
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GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome
(1792 downloads)
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01 Jul 2016
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Impact of socioeconomic status on disease phenotype, genomic landscape and outcomes in myelodysplastic syndromes
(1403 downloads)
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01 Jul 2016
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Mutations in histone modulators are associated with prolonged survival during azacitidine therapy
(1920 downloads)
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19 Apr 2016
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The European Hematology Association Roadmap for European Hematology Research: a consensus document
(1576 downloads)
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29 Feb 2016
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Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts
(1760 downloads)
Popular
17 Nov 2015
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Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome
(1637 downloads)
Popular
27 Oct 2015
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Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry
(1734 downloads)
Popular
21 Oct 2015
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SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts
(2041 downloads)
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21 Oct 2015
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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells
(1200 downloads)
Popular
01 Aug 2015
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High-throughput mutational screening adds clinically important information in myelodysplastic syndromes and secondary or therapy-related acute myeloid leukemia
(1686 downloads)
Popular
01 Jun 2015
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Self-perception of symptoms of anemia and fatigue before and after blood transfusions in patients with myelodysplastic syndromes
(1859 downloads)
Popular
01 Apr 2015
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Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes
(1294 downloads)
Popular
09 Jan 2015
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Specific scoring systems to predict survival of patients with high-risk myelodysplastic syndrome (MDS) and de novo acute myeloid leukemia (AML) after intensive antileukemic treatment based on results of the EORTC-GIMEMA AML-10 and intergroup CRIANT studie
(1527 downloads)
Popular
01 Jan 2015
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Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes
(1273 downloads)
Popular
01 Jan 2015
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Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study
(1719 downloads)
Popular
21 Nov 2014
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Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia
(1419 downloads)
Popular
28 Aug 2014
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Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes
(1264 downloads)
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04 Aug 2014
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A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome
(1849 downloads)
Popular
19 Jun 2014
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Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
(1284 downloads)
Popular
16 Jun 2014
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A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine
(1654 downloads)
Popular
14 Jun 2014
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A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome
(1317 downloads)
Popular
01 Jun 2014
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p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q)
(1365 downloads)
Popular
01 Jun 2014
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Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
(1897 downloads)
Popular
15 May 2014
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Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial
(1769 downloads)
Popular
07 May 2014
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Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation
(1623 downloads)
Popular
21 Feb 2014
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Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients
(1628 downloads)
Popular
21 Feb 2014
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Challenges of phase III trial design for novel treatments in diseases with no standard treatment: the AZA-001 myelodysplasia study model
(1277 downloads)
Popular
01 Feb 2014
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Clinical and biological implications of driver mutations in myelodysplastic syndromes
(2062 downloads)
Popular
21 Nov 2013
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Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet
(1355 downloads)
Popular
24 Oct 2013
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Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes
(1604 downloads)
Popular
01 Oct 2013
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Role of reduced-intensity conditioning allogeneic hematopoietic stem-cell transplantation in older patients with de novo myelodysplastic syndromes: an international collaborative decision analysis
(1159 downloads)
Popular
20 Jul 2013
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A multivariate analysis of the relationship between response and survival among patients with higher-risk myelodysplastic syndromes treated within azacitidine or conventional care regimens in the randomized AZA-001 trial
(1191 downloads)
Popular
01 Jul 2013
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Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions
(1330 downloads)
Popular
01 May 2013
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The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts
(1148 downloads)
Popular
01 Apr 2013
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Lenalidomide does not increase AML progression risk in RBC transfusion-dependent patients with Low- or Intermediate-1-risk MDS with del(5q): a comparative analysis
(1223 downloads)
Popular
01 Apr 2013
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Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1
(1221 downloads)
Popular
01 Mar 2013
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Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group
(1063 downloads)
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01 Mar 2013
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Bone marrow dendritic cells are reduced in patients with high-risk myelodysplastic syndromes
(1423 downloads)
Popular
01 Mar 2013
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Downregulation but lack of promoter hypermethylation or somatic mutations of the potential tumor suppressor CXXC5 in MDS and AML with deletion 5q
(1274 downloads)
Popular
01 Mar 2013
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Evaluation of Azacitidine in transfusion-dependent, Epo-refractory patients with lower-risk MDS
( pdf, 83 KB )
(1986 downloads)
Popular
18 Jun 2012
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Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML
(1255 downloads)
Popular
05 Jan 2012
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Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
(1285 downloads)
Popular
08 Dec 2011
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Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks
(1197 downloads)
Popular
17 Nov 2011
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Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
(1188 downloads)
Popular
13 Oct 2011
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Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
(1158 downloads)
Popular
01 Oct 2011
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Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes
(1086 downloads)
Popular
15 Jun 2011
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TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression
(1242 downloads)
Popular
20 May 2011
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Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities
(1511 downloads)
Popular
31 Mar 2011
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Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes
(1172 downloads)
Popular
01 Dec 2010
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Significance of JAK2 and TET2 mutations in myelodysplastic syndromes
(1693 downloads)
Popular
18 Sep 2010
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Persistent malignant stem cells in del(5q) myelodysplasia in remission
(1264 downloads)
Popular
09 Sep 2010
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Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine
(1308 downloads)
Popular
01 Aug 2010
pdf
Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy
(1484 downloads)
Popular
20 May 2010
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Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C
(1169 downloads)
Popular
01 Apr 2010
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Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
(1199 downloads)
Popular
01 Feb 2010
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Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression
(1106 downloads)
Popular
01 Dec 2009
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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
(1605 downloads)
Popular
18 Feb 2009
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Erythropoietin and G-CSF treatment associated with improved survival in myelodysplastic syndrome
(1666 downloads)
Popular
18 Sep 2008
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Supportive care, growth factors, and new therapies in myelodysplastic syndromes
(1624 downloads)
Popular
18 Sep 2008
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Azacitidine prolongs overall survival and reduces infections and hospitalizations in patients with WHO-defined acute myeloid leukaemia compared with conventional care regimens: an update
(1156 downloads)
Popular
01 Jan 2008
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The effects of continued azacitidine treatment cycles on response in higher risk patients with myelodysplastic syndromes: an update
(1128 downloads)
Popular
01 Jan 2008
pdf
Negative Effect of DNA Hypermethylation on the Outcome of Intensive Chemotherapy in Older Patients with High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia following Myelodysplastic Syndrome
(1430 downloads)
Popular
01 Dec 2007
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The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes
(1051 downloads)
Popular
15 Oct 2007
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Antithymocyte globulin and cyclosporine A as combination therapy for low-risk non-sideroblastic myelodysplastic syndromes
(1373 downloads)
Popular
18 Sep 2006
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Antiapoptotic role of growth factors in the myelodysplastic syndromes: concordance between in vitro and in vivo observations
(1028 downloads)
Popular
01 Sep 2005
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Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes
(1005 downloads)
Popular
01 Jul 2005
pdf
Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF
(1503 downloads)
Popular
19 Apr 2005
pdf
The WHO classification of MDS does make a difference
(1466 downloads)
Popular
01 May 2004
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No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease
(1325 downloads)
Popular
24 Apr 2003
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A validated decision model for treating the anaemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life
(1382 downloads)
Popular
23 Sep 2002
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Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8
(1065 downloads)
Popular
01 Jul 2002
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Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level
(1044 downloads)
Popular
15 Sep 2000
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