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default Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance (22 downloads)
default Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease (16 downloads)
default The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes (28 downloads)
default Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel (91 downloads)
default Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome (17 downloads)
default Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations (18 downloads)
default Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice (28 downloads)
default Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data (26 downloads)
default Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia (11 downloads)
default Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality (170 downloads)
default GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome (203 downloads)
default Mutations in histone modulators are associated with prolonged survival during azacitidine therapy (395 downloads)
default The European Hematology Association Roadmap for European Hematology Research: a consensus document (25 downloads)
default Aberrant splicing of genes involved in haemoglobin synthesis and impaired terminal erythroid maturation in SF3B1 mutated refractory anaemia with ring sideroblasts (361 downloads)
default Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome (172 downloads)
default Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry (287 downloads)
default SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts (457 downloads)
default High-throughput mutational screening adds clinically important information in myelodysplastic syndromes and secondary or therapy-related acute myeloid leukemia (347 downloads)
default Self-perception of symptoms of anemia and fatigue before and after blood transfusions in patients with myelodysplastic syndromes (352 downloads)
default Specific scoring systems to predict survival of patients with high-risk myelodysplastic syndrome (MDS) and de novo acute myeloid leukemia (AML) after intensive antileukemic treatment based on results of the EORTC-GIMEMA AML-10 and intergroup CRIANT studie (276 downloads)
default Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study (350 downloads)
default Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes (8 downloads)
default A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome (431 downloads)
default A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine (377 downloads)
default Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo (427 downloads)
pdf Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial (363 downloads)
default Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation (353 downloads)
default Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients (318 downloads)
default Clinical and biological implications of driver mutations in myelodysplastic syndromes (403 downloads)
default Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes (334 downloads)
pdf Evaluation of Azacitidine in transfusion-dependent, Epo-refractory patients with lower-risk MDS ( pdf, 83 KB ) (439 downloads)
default Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks (5 downloads)
pdf Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities (307 downloads)
pdf Significance of JAK2 and TET2 mutations in myelodysplastic syndromes (367 downloads)
pdf Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy (309 downloads)
pdf Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study (296 downloads)
pdf Erythropoietin and G-CSF Treatment Associated with Improved Survival in Myelodysplastic Syndrome (367 downloads)
pdf Supportive care, growth factors, and new therapies in myelodysplastic syndromes (341 downloads)
pdf Negative Effect of DNA Hypermethylation on the Outcome of Intensive Chemotherapy in Older Patients with High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia following Myelodysplastic Syndrome (226 downloads)
pdf Antithymocyte globulin and cyclosporine A as combination therapy for low-risk non-sideroblastic myelodysplastic syndromes (278 downloads)
pdf Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF (330 downloads)
pdf The WHO classification of MDS does make a difference (324 downloads)
pdf No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease (255 downloads)
pdf A validated decision model for treating the anaemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life (278 downloads)